Last time royal cancelled all of empresses itinerary and put a new Cuba one up. Then if I remember right royal promised to build them a new pier and port facility by a certain time frame and of course royal didn't die to the reimplemented sanctions. So Cuba sued royal for not fulfilling it.
I don't think any cruise lines will invest there due to the fact the sanctions could be reinstated that fast.
Maybe small ships with heavy prices will jump on the opportunity while it's there.